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  • Human DOT1L/KMT4 recombinant protein

Human DOT1L/KMT4 recombinant protein

Cat.#: 500138

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Product Information

  • Product Name
    Human DOT1L/KMT4 recombinant protein
  • Documents
  • Description
    Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.
  • Protein name
    Histone-lysine N-methyltransferase, H3 lysine-79 specific
  • Protein short names
    AW907654; DKFZP586P1823; MDOT1; DOT1; KMT4; DOT1L; KIAA1814; A630076O07
  • Uniprot ID
    Q8TEK3
  • Gene Name
    DOT1L; KIAA1814; KMT4
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human DOT1L (NP_115871.1) N-terminal segment (Gly 2-Lys 416) was expressed and purified, with two additional amino acids (Gly & Pro) at the N-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human DOT1L comprises 417 amino acids and has a predicted molecular mass of 47.6 kDa. It migrates as an approximately 50 kDa band in SDS-PAGE under reducing conditions as predicted.
  • Purity
    > 90 % as determined by SDS-PAGE
  • Validations

    Human DOT1L / KMT4 Protein SDS-PAGE

    Human DOT1L / KMT4 Protein SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"