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Product Name
Human GOPC / PIST (His Tag) recombinant protein
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Description
Plays a role in intracellular protein trafficking and degradation. May regulate CFTR chloride currents and acid-induced ASIC3 currents by modulating cell surface expression of both channels. May also regulate the intracellular trafficking of the ADR1B receptor. May play a role in autophagy. Overexpression results in CFTR intracellular retention and degradation in the lysosomes.
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Protein name
Golgi-associated PDZ and coiled-coil motif-containing protein
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Protein short names
GOLGI ASSOCIATED PDZ AND COILED-COIL MOTIF CONTAINING; GOLGI-ASSOCIATED PDZ AND COILED-COIL MOTIF-CONTAINING PROTEIN; DJ94G16.2; FIG; FUSED IN GLIOBLASTOMA; PDZ PROTEIN INTERACTING SPECIFICALLY WITH TC10; GOLGI-ASSOCIATED PDZ AND COILED-COIL MOTIF CONTAINING; PDZ/COILED-COIL DOMAIN BINDING PARTNER FOR THE RHO-FAMILY GTPASE TC10; 2210402P09RIK; PDZ DOMAIN-CONTAINING PROTEIN PIST; AI844555; GOPC1; GOLGI ASSOCIATED PDZ AND COILED-COIL MOTIF CONTAINING PROTEIN; GOPC; CAL; CFTR-ASSOCIATED LIGAND; DJ94G16.2 PIST; PIST
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Uniprot ID
Q9HD26
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Gene Name
GOPC; CAL; FIG
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human GOPC (Q9HD26-1) (Ile286-Tyr462) was expressed with a polyhistide tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human GOPC consists of 192 amino acids and predicts a molecular mass of 21.1 KDa. It migrates as an approximately 25-30 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human GOPC / PIST Protein (His Tag) SDS-PAGE
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