Human LGALS3 recombinant protein
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
Protein short names
GALECTIN-3; LGALS2; GAL3; GALBP; LGALS3; GBP; L31; L-34; MAC-2; MAC2; CBP35; GALIG
A DNA sequence encoding the human Galectin3 (P17931) (Met 1-Ile 250) was expressed and purified.
The recombinant human Galectin3 consisting of 250 amino acids and has a calculated molecular mass of 26.1 kDa. It migrates as an approximately 30 kDa band in SDS-PAGE under reducing conditions.
> 97 % as determined by SDS-PAGE
Measured by its ability to agglutinate human red blood cells. The ED50 for this effect is typically 3-15 μg/ml.
Human Galectin-3 / LGALS3 Protein, Low Endotoxin SDS-PAGE
Related Products / Services
- Recombinant Proteins
- cDNA Clones
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