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Product Name
Mouse Follistatin (Fc Tag) recombinant protein
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Description
Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH).
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Protein name
Follistatin
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Protein short names
FS; AL033346; FST; FOLLISTATIN
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Uniprot ID
P47931
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Gene Name
Fst
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Source/Expression Host
CHO Stable Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse FST (P47931) (Met 1-Asn 317) was expressed with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse FST comprises 528 amino acids and has a predicted molecular mass of 58.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of the protein is approximately 66 kDa due to glycosylation.
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Purity
> 90 % as determined by SDS-PAGE
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Activity
Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation.
The ED50 for this effect is typically 40-200 ng/mL in the presence of 10 ng/mL rhActivin A. -
Validations
Mouse Follistatin / FST (FS288) Protein (Fc Tag) SDS-PAGE
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