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  • Canine aFGF / FGF1 recombinant protein

Canine aFGF / FGF1 recombinant protein

Cat.#: 501527

Special Price 77.1 USD

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Product Information

  • Product Name
    Canine aFGF / FGF1 recombinant protein
  • Documents
  • Description
    aFGF, also known as FGF1 and HBGF-1, is a member of the fibroblast growth factor family. The biological activity of aFGF protein is exerted through binding to four high affinity cell surface receptors (FGFR1-4), which results in receptor dimerization and transphosphorylation in the tyrosine kinase domain. aFGF protein shows a wide range of endocrine-like activities. As a multiple function growth factor, this protein is involved in embryo development and tissue repair. Additionally, this protein is considered to function in several important physiological and pathological processes, such as embryonic development, morphogenesis, angiogenesis, wound healing and atheromatosis, carcinogenesis, development, and invasion of cancer.
  • Protein name
    Fibroblast growth factor
  • Protein short names
    FGF
  • Uniprot ID
    J9NTP4
  • Gene Name
    FGF1
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the canine FGF1 (XP_849274.1) (Phe16-Asp155) was expressed with a N-terminal Met.
  • Protein Species
    Canine
  • Molecular weight
    The recombinant canine FGF1 comprises 141 amino acids and has a predicted molecular mass of 16 kDa. The apparent molecular mass of the protein is approximately 16 kDa in SDS-PAGE under reducing conditions.
  • Purity
    > 90 % as determined by SDS-PAGE
  • Activity
    Measured in a cell proliferation assay using Balb/c 3T3 mouse embryonic fibroblasts.
    The ED50 for this effect is typically 0.05-0.3 ng/ml.
  • Validations

    Canine aFGF / FGF1 Protein SDS-PAGE

    Canine aFGF / FGF1 Protein SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"