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  • EDG2 Antibody (N-term)

EDG2 Antibody (N-term)

Cat.#: 136678

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Special Price 372.6 USD

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Product Information

  • Product Name
    EDG2 Antibody (N-term)
  • Documents
  • Description
    Purified Rabbit Polyclonal Antibody (Pab)
  • Tested applications
    WB, ELISA
  • Species reactivity
    Human
  • Alternative names
    EDG2 antibody; LPA1 antibody; Lysophosphatidic acid receptor 1 antibody; LPA receptor 1 antibody; LPA-1 antibody; Lysophosphatidic acid receptor Edg-2 antibody; LPAR1 antibody; EDG2 antibody; LPA1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This EDG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human EDG2.
  • Clonality
    Polyclonal
  • Formulation
    Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
  • Storage instructions
    Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
  • Applications
    WB: 1:1000
  • Validations

    The anti-EDG2 N-term Antibody (Cat.#136678) is used in Western blot to detect EDG2 in A375 lysate.

    The anti-EDG2 N-term Antibody (Cat.#136678) is used in Western blot to detect EDG2 in A375 lysate.

  • Background
    Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Stimulates phospholipase C (PLC) activity in a manner that is dependent on RALA activation.
  • References
    • Boucharaba A, Serre CM, Guglielmi J, Bordet JC, Clézardin P, Peyruchaud O. The type 1 lysophosphatidic acid receptor is a target for therapy in bone metastases. Proceedings of the National Academy of Sciences of the United States of America. 103(25):9643-8. 2006.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"