-
Product Name
Rat E-Selectin/CD62e/SELE (Fc Tag) recombinant protein
- Documents
-
Description
Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis (By similarity).
-
Protein name
E-selectin
-
Protein short names
E-SELECTIN; LECAM2; SELE; ELAM1; CD62E; ESEL; ELAM; RP1-117P20.2; ELAM-1
-
Uniprot ID
P98105
-
Gene Name
Sele; Elam-1
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the rat SELE (NP_620234.1) (Met1-Pro494) was expressed with the Fc region of human IgG1 at the C-terminus.
-
Protein Species
Rat
-
Molecular weight
The recombinant rat SELE/Fc is a disulfide-linked homodimer. The reduced monomer comprises 714 amino acids and has a predicted molecular mass of 78.8 kDa. The apparent molecular mass of the protein is approximately 114-119 kDa in SDS-PAGE under reducing conditions.
-
Purity
> 95 % as determined by SDS-PAGE
-
Activity
Measured by the ability of the immobilized protein to support the adhesion of U937 cells.
When 5 x 10E4 cells/well are added to SELE coated plates (2 μg/mL and 100 μL/well), approximately >85% cells will adhere specifically after 60 minutes at 37℃. -
Validations
Rat E-Selectin / CD62e / SELE Protein (Fc Tag) SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"