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  • Rat E-Selectin/CD62e/SELE (Fc Tag) recombinant protein

Rat E-Selectin/CD62e/SELE (Fc Tag) recombinant protein

Cat.#: 501235

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Product Information

  • Product Name
    Rat E-Selectin/CD62e/SELE (Fc Tag) recombinant protein
  • Documents
  • Description
    Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis (By similarity).
  • Protein name
    E-selectin
  • Protein short names
    E-SELECTIN; LECAM2; SELE; ELAM1; CD62E; ESEL; ELAM; RP1-117P20.2; ELAM-1
  • Uniprot ID
    P98105
  • Gene Name
    Sele; Elam-1
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the rat SELE (NP_620234.1) (Met1-Pro494) was expressed with the Fc region of human IgG1 at the C-terminus.
  • Protein Species
    Rat
  • Molecular weight
    The recombinant rat SELE/Fc is a disulfide-linked homodimer. The reduced monomer comprises 714 amino acids and has a predicted molecular mass of 78.8 kDa. The apparent molecular mass of the protein is approximately 114-119 kDa in SDS-PAGE under reducing conditions.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Activity
    Measured by the ability of the immobilized protein to support the adhesion of U937 cells.
    When 5 x 10E4 cells/well are added to SELE coated plates (2 μg/mL and 100 μL/well), approximately >85% cells will adhere specifically after 60 minutes at 37℃.
  • Validations

    Rat E-Selectin / CD62e / SELE Protein (Fc Tag) SDS-PAGE

    Rat E-Selectin / CD62e / SELE Protein (Fc Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"