-
Product Name
Cynomolgus CD86 (His tag) recombinant protein
- Documents
-
Description
T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. It is highly expressed on activated antigen presenting cells. CD86 involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. It is expressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endocytosis and lysosomal degradation.
-
Protein name
CD86 molecule(CD86)
-
Uniprot ID
H9ZFI8
-
Source/Expression Host
E.coli
-
Expression Plasmid/cDNA
A DNA sequence encoding the Cynomolgus CD86 Tyr31-Pro247 is expressed with a 6His tag at the C-terminus.
-
Protein Species
Cynomolgus
-
Purity
>95% as determined by SDS-PAGE.
-
Validations
Cynomolgus CD86 (His tag) recombinant protein
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"