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  • CRMP2 antibody
  • CRMP2 antibody
  • CRMP2 antibody
  • CRMP2 antibody

CRMP2 antibody

Cat.#: 109570

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Product Information

  • Product Name
    CRMP2 antibody
  • Documents
  • Description
    CRMP2 Rabbit Polyclonal antibody. Positive IHC detected in human colon cancer tissue. Positive IF detected in HepG2 cells. Positive WB detected in human heart tissue. Observed molecular weight by Western-blot: 62 kDa
  • Tested applications
    ELISA, WB, IHC, IF
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    CRMP 2 antibody; CRMP2 antibody; DHPRP2 antibody; dihydropyrimidinase like 2 antibody; DPYSL2 antibody; DRP 2 antibody; DRP2 antibody; N2A3 antibody; ULIP 2 antibody; ULIP2 antibody; Unc 33 like phosphoprotein 2 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of CRMP2 recombinant protein (Accession Number: BC067109). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:1000

    IHC: 1:20-1:200

    IF: 1:20-1:200

  • Validations

    human heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:109570(DPYSL2 antibody) at dilution of 1:300

    human heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:109570(DPYSL2 antibody) at dilution of 1:300

    Immunohistochemical of paraffin-embedded human colon cancer using Catalog No:109570(DPYSL2 antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human colon cancer using Catalog No:109570(DPYSL2 antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human colon cancer using Catalog No:109570(DPYSL2 antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemical of paraffin-embedded human colon cancer using Catalog No:109570(DPYSL2 antibody) at dilution of 1:50 (under 40x lens)

    Immunofluorescent analysis of HepG2 cells, using DPYSL2 antibody Catalog No:109570 at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).

    Immunofluorescent analysis of HepG2 cells, using DPYSL2 antibody Catalog No:109570 at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).

  • Background
    Dihydropyrimidinase-like 2 (Dpysl2), a protein involved in neuronal differentiation and axonal guidance is found altered in various nervous system diseases (PMID:19524114). It is also named as CRMP2, ULIP2 and belongs to hydantoinase/dihydropyrimidinase subfamily. The phosphorylation of the particular portion carboxyl-terminal to the basic region of DPYSL2 may play an important role in regulating its activity, and may be involved in the formation of degenerating neurites in AD brain(PMID:10757975).
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"