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  • Mouse CD200R1 (His & Fc Tag) recombinant protein

Mouse CD200R1 (His & Fc Tag) recombinant protein

Cat.#: 500001

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Product Information

  • Product Name
    Mouse CD200R1 (His & Fc Tag) recombinant protein
  • Documents
  • Description
    Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of proinflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli.
  • Protein name
    Cell surface glycoprotein CD200 receptor 1
  • Protein short names
    CD200R; OX2R; MOX2R; HCRTR2; CD200R1
  • Uniprot ID
    Q9ES57
  • Gene Name
    Cd200r1; Mox2r; Ox2r
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the extracellular domain (Met 1-Pro 238) of mouse CD200R1 (NP_067300.1) precursor was fused with the Fc region of human IgG1 at the C-terminus.
  • Protein Species
    Mouse
  • Molecular weight
    The recombinant mouse CD200R1/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer consists of 462 amino acids and has a predicted molecular mass of 51.3 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmCD200R1/Fc monomer is approximately 90-100 kDa due to glycosylation.
  • Purity
    > 97 % as determined by SDS-PAGE
  • Activity
    Measured by its binding ability in a functional ELISA. Immobilized recombinant mouse CD200 at 1 μg/ml (100 μl/well) can bind mouse CD200R1/Fc with a linear range of 1.5-200 ng/ml.
  • Validations

    Mouse CD200R1 Protein (His & Fc Tag) SDS-PAGE

    Mouse CD200R1 Protein (His & Fc Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"