Human CD27 (His & Fc Tag) recombinant protein

Cat.#: 502095

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Product Information

  • Product Name
    Human CD27 (His & Fc Tag) recombinant protein
  • Documents
  • Description
    Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.
  • Protein name
    CD27 antigen
  • Protein short names
    TNFRSF7; MGC20393; T14; TP55; CD27; S152; S152.LPFS2
  • Uniprot ID
    P26842
  • Gene Name
    CD27; TNFRSF7
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the extracellular domain (Met 1-Ile 192) of human CD27 (NP_001233.1) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the carboxy-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant mature human CD27/Fc is a disulfide-linked homodimeric protein. The reduced monomer comprises 420 amino acids and has a calculated molecular mass of 47.2 kDa. As a result of glycosylation, the monomer migrates as an approximately 65 kDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Activity
    Measured by its ability to bind with recombinant human CD70.
    Immobilized recombinant human CD27 at 2 μg/ml (100 μl/well) can bind biotinylated human CD70 with a linear range of 0.39-12.5 ng/ml.
  • Validations

    Human CD27 / TNFRSF7 Protein (His & Fc Tag) SDS-PAGE

    Human CD27 / TNFRSF7 Protein (His & Fc Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"