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Product Name
Human PPP3R1 (His Tag) recombinant protein
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Description
Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.
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Protein name
Calcineurin subunit B type 1
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Protein short names
REGULATORY SUBUNIT B; REGULATORY SUBUNIT B (19KD); ALPHA ISOFORM; PROTEIN PHOSPHATASE 2B REGULATORY SUBUNIT B ALPHA; TYPE I); TYPE I (19KDA); PP2B BETA 1; CNB; PROTEIN PHOSPHATASE 2B REGULATORY SUBUNIT 1; CNB1; CANB1; 19KDA; RP23-32H19.1; ALPHA ISOFORM (CALCINEURIN B; CALCINEURIN SUBUNIT B TYPE 1; CALCINEURIN B; MCIP1; CALNB1; PROTEIN PHOSPHATASE 3 REGULATORY SUBUNIT B ALPHA; PROTEIN PHOSPHATASE 3 (FORMERLY 2B)
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Uniprot ID
P63098
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Gene Name
PPP3R1; CNA2; CNB
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human PPP3R1 (P63098) (Gly2-Val170) was fused with a polyhistide tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human PPP3R1 consists of 187 amino acids and has a calculated molecular mass of 21.4 kDa. The recombinant protein migrates as an approximately 20 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 87 % as determined by SDS-PAGE
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Activity
Using the Octet RED System, the affinity constant (Kd) of human PPP3R1-His bound to Human PPIA-His (Cat:501254) was 6 nM.
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Validations
Human PPP3R1 Protein (His Tag) SDS-PAGE
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