Human BPI (His Tag) recombinant protein
The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.
Bactericidal permeability-increasing protein
Protein short names
MEMBER 1; CAP 57; RP23-407H16.3; RECOMBINANT BPI HOLOPROTEIN; RBPI BPI FOLD CONTAINING FAMILY D; BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN; BACTERICIDAL PERMEABILITY-INCREASING PROTEIN; RBPI; BPIFD1; RP13-218F6_A.1; 9230105K17RIK
A DNA sequence encoding the human BPI (P17213) (Met1-Lys487) with a C-terminal polyhistidine tag was expressed.
The recombinant human BPI comprises 467 amino acids and has a predicted molecular mass of 52.1 kDa.
> 85 % as determined by SDS-PAGE
Human BPI Protein (His Tag) SDS-PAGE
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