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Product Name
Mouse ASGPR1 (His Tag) recombinant protein
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Description
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
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Protein name
Asialoglycoprotein receptor 1
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Protein short names
ASGR1; ASGPR1; HS.12056; HL-1; ASGR; ASGR-1; CLEC4H1; RP23-172M21.2; ASGPR
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Uniprot ID
P34927
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Gene Name
Asgr1; Asgr-1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the extracellular domain (Ser 60-Asn 284) of mouse ASGPR1 (NP_033844.1) was expressed with a N-terminal polyhistidine tag.
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Protein Species
Mouse
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Molecular weight
The secreted recombinant mouse ASGR1 consists of 241 amino acids and has a calculated molecular mass of 28 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 40-45 kDa protein in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Mouse ASGPR1 / ASGR1 Protein (His Tag) SDS-PAGE
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