Anti-Ephrin-B1/EFNB1 antibody

Anti-Ephrin-B1/EFNB1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit polyclonal to Ephrin-B1/EFNB1

ELISA, WB, IP

Rat Ephrin-B1 / EFNB1

Epl2 antibody; EFL-3 antibody; Elk-L antibody; Eplg2 antibody; Lerk2 antibody; Stra1 antibody; Cek5-L antibody; LERK-2 antibody; CFND antibody; CFNS antibody; EFB1 antibody; EFL3 antibody; EPLG2 antibody; Elk-L antibody; LERK2 antibody; Cek5-L antibody; CFND antibody; CFNS antibody; EFL3 antibody; EFL-3 antibody; EFNB1 antibody; Efnb1 antibody; Elk-L antibody; Elk-L antibody; Ephrin B1 antibody; Ephrin-B1 antibody; Epl2 antibody; EPLG2 antibody; Eplg2 antibody; Lerk2 antibody; LERK2 antibody; LERK-2 antibody; MGC8782 antibody; RP23-110A15.1 antibody; RP3-496G1.1 antibody; Stra1 antibody

Rabbit IgG

Produced in rabbits immunized with purified, recombinant Rat Ephrin-B1 / EFNB1 (rh Ephrin-B1 / EFNB1; P52796; Met1-Thr229). Ephrin-B1 / EFNB1 specific IgG was purified by Rat Ephrin-B1 / EFNB1 affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Ephrin-B1 also known as EFNB1, is a member of the ephrin family. The transmembrane- associated ephrin ligands and their Eph family of receptor tyrosine kinases are expressed by cells of the SVZ. Eph/ephrin interactions are implicated in axon guidance, neural crest cell migration, establishment of segmental boundaries, and formation of angiogenic capillary plexi. Eph receptors and ephrins are divided into two subclasses, A and B, based on binding specificities. Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: ephrin-A ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. An exception is the EphA4 receptor, which binds both subclasses of ephrins. EphrinB1 and B class Eph receptors provide positional cues required for the normal morphogenesis of skeletal elements. Another malformation, preaxial polydactyly, was exclusively seen in heterozygous females in which expression of the X-linked ephrinB1 gene was mosaic, so that ectopic EphB-ephrinB1 interactions led to restricted cell movements and the bifurcation of digital rays.

• Davy A, et al. (2004) Ephrin-B1 forward and reverse signaling are required during mouse development. Genes Dev. 18(5): 572-83.
• Compagni A, et al. (2003) Control of skeletal patterning by ephrinB1-EphB interactions. Dev Cell. 5(2): 217-30.
• Wieland I, et al. (2004) Mutations of the ephrin-B1 gene cause craniofrontonasal syndrome. Am J Hum Genet. 74(6): 1209-15.