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  • Anti-EGFL6 / EGF-L6 antibody

Anti-EGFL6 / EGF-L6 antibody

Cat.#: 100446

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Product Information

  • Product Name
    Anti-EGFL6 / EGF-L6 antibody
  • Documents
  • Description
    Rabbit polyclonal to EGFL6 / EGF-L6
  • Tested applications
    ELISA
  • Species reactivity
    Mouse EGFL6 / EGF-L6
  • Alternative names
    W80 antibody; MAEG antibody; Maeg antibody; EGF-like-domain antibody; multiple 6 antibody; EGFL6 antibody; PP648 antibody; MAEG antibody; W80 antibody; EGF repeat-containing protein 6 antibody; EGF-like protein 6 antibody; MAM and EGF domain containing antibody; MAM and EGF domains-containing gene protein antibody; epidermal growth factor-like protein 6 antibody; EGF-like-domain antibody; multiple 6 antibody; Egfl6 antibody; RP23-408K4.7 antibody; Maeg antibody; EGF-like protein 6 antibody; MAM and EGF domains-containing gene protein antibody; epidermal growth factor-like protein 6 antibody
  • Immunogen
  • Isotype
    Rabbit IgG
  • Preparation
    Produced in rabbits immunized with purified, recombinant Mouse EGFL6 / EGF-L6 (rM EGFL6 / EGF-L6; NP_062270.1; Thr287-Gly550). Total IgG was purified by Protein A affinity chromatography.
  • Clonality
    Polyclonal
  • Formulation
    0.2 μm filtered solution in PBS
  • Storage instructions
    This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
    Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
  • Applications

    ELISA: 0.5-1 μg/ml

    This antibody can be used at 0.5-1 μg/ml with the appropriate secondary reagents to detect Mouse EGFL6 / EGF-L6.

  • Validations
  • Background
    EGFL6, also known as EGF-L6, belongs to the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. EGFL6 contains a signal peptide, suggesting that it is secreted; an EGF repeat region consisting of 4 complete EGF-like repeats and 1 partial EGF-like repeat, 3 of which have a calcium-binding consensus sequence; an arg-gly-asp integrin association motif; and a MAM domain, which is believed to have an adhesive function. EGFL6 gene is expressed early during development, and its expression has been detected in lung and meningioma tumors.
  • References
    • Kimura K. et al., 2006, Genome Res. 16 (1): 55-65.
    • Lee SH. et al., 2008, Pathology. 40 (1): 95-7.
    • Oberauer R. et al., 2010, Mol Cell Biochem. 343 (1-2): 257-69.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"