NovoPro
Cart 2
  • Anti-EFNB2A / Ephrin B2a antibody

Anti-EFNB2A / Ephrin B2a antibody

Cat.#: 105592

Special Price 145.0 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Anti-EFNB2A / Ephrin B2a antibody
  • Documents
  • Description
    Rabbit polyclonal to EFNB2A / Ephrin B2a
  • Tested applications
    ELISA
  • Species reactivity
    Danio rerio (zebrafish) EFNB2A / Ephrin B2a
  • Alternative names
    CH211-149B20.1 antibody; efnb2 antibody; id:ibd5072 antibody
  • Immunogen
  • Isotype
    Rabbit IgG
  • Preparation
    Produced in rabbits immunized with purified, recombinant Danio rerio (zebrafish) EFNB2A / Ephrin B2a (rh EFNB2A / Ephrin B2a; O73874; Met 1-Ala222). EFNB2A / Ephrin B2a specific IgG was purified by Danio rerio (zebrafish) EFNB2A / Ephrin B2a affinity chromatography.
  • Clonality
    Polyclonal
  • Formulation
    0.2 μm filtered solution in PBS
  • Storage instructions
    This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
    Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
  • Applications

    ELISA: 0.1-0.2 μg/mL

    This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Danio rerio (zebrafish) EFNB2A / Ephrin B2a. The detection limit for Danio rerio (zebrafish) EFNB2A / Ephrin B2a is < 0.039 ng/well.

  • Validations
  • Background
    Efnb2a, also known as ephrin B2a, belongs to the ephrin family. Members of this family are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Efnb2a binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Efnb2a, together with ephb4 may play a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration.
  • References
    • Shaw KM. et al., 2006, Dev Dyn. 235 (7): 1753-60.
    • Kemp HA. et al., 2009, Dev Biol. 327 (2): 313-26.
    • Patten SA. et al., 2012, PLoS One. 7 (2): e31650.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"