Anti-EFNB2A / Ephrin B2a antibody
Rabbit polyclonal to EFNB2A / Ephrin B2a
Danio rerio (zebrafish) EFNB2A / Ephrin B2a
CH211-149B20.1 antibody; efnb2 antibody; id:ibd5072 antibody
Produced in rabbits immunized with purified, recombinant Danio rerio (zebrafish) EFNB2A / Ephrin B2a (rh EFNB2A / Ephrin B2a; O73874; Met 1-Ala222). EFNB2A / Ephrin B2a specific IgG was purified by Danio rerio (zebrafish) EFNB2A / Ephrin B2a affinity chromatography.
0.2 μm filtered solution in PBS
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Danio rerio (zebrafish) EFNB2A / Ephrin B2a. The detection limit for Danio rerio (zebrafish) EFNB2A / Ephrin B2a is < 0.039 ng/well.
Efnb2a, also known as ephrin B2a, belongs to the ephrin family. Members of this family are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Efnb2a binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Efnb2a, together with ephb4 may play a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration.
- Shaw KM. et al., 2006, Dev Dyn. 235 (7): 1753-60.
- Kemp HA. et al., 2009, Dev Biol. 327 (2): 313-26.
- Patten SA. et al., 2012, PLoS One. 7 (2): e31650.
Related Products / Services
- Recombinant Proteins
- cDNA Clones
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"