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  • Anti-CD48/SLAMF2 antibody
  • Anti-CD48/SLAMF2 antibody

Anti-CD48/SLAMF2 antibody

Cat.#: 101884

Special Price 145.0 USD

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Product Information

  • Product Name
    Anti-CD48/SLAMF2 antibody
  • Documents
  • Description
    Rabbit polyclonal to CD48/SLAMF2
  • Tested applications
    ELISA, WB, IP
  • Species reactivity
    Human CD48 / BCM1
  • Alternative names
    BCM1 antibody; BLAST antibody; hCD48 antibody; mCD48 antibody; BLAST1 antibody; SLAMF2 antibody; MEM-102 antibody; BCM1 antibody; BLAST antibody; Bcm-1 antibody; BLAST1 antibody; SLAMF2 antibody; Sgp-60 antibody; BLAST-1 antibody; MEM-102 antibody; AI449234 antibody; AW610730 antibody; AI449234 antibody; AW610730 antibody; BCM1 antibody; BCM1 antibody; Bcm-1 antibody; BLAST antibody; BLAST antibody; BLAST1 antibody; BLAST1 antibody; BLAST-1 antibody; Cd48 antibody; CD48 antibody; hCD48 antibody; mCD48 antibody; MEM-102 antibody; MEM-102 antibody; Sgp-60 antibody; SLAMF2 antibody; SLAMF2 antibody
  • Immunogen
  • Isotype
    Rabbit IgG
  • Preparation
    Produced in rabbits immunized with purified, recombinant Human CD48 (rh CD48; NP_001769.2; Met 1-Ser 220). CD48 specific IgG was purified by human CD48 affinity chromatography.
  • Clonality
    Polyclonal
  • Formulation
    0.2 μm filtered solution in PBS with 5% trehalose
  • Storage instructions
    This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
    Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
  • Applications

    WB: 20-50 μg/mL

    ELISA: 0.5-1.0 μg/mL

    This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect Human CD48. The detection limit for Human CD48 is 0.00245 ng/well.

    IP: 1-4 μg/mg of lysate

  • Validations

    CD48 / SLAMF2 / BCM1 Antibody, Rabbit PAb, Antigen Affinity Purified, Western blot

    CD48 / SLAMF2 / BCM1 Antibody, Rabbit PAb, Antigen Affinity Purified, Western blot

    CD48 / SLAMF2 / BCM1 Antibody, Rabbit PAb, Antigen Affinity Purified

    CD48 / SLAMF2 / BCM1 Antibody, Rabbit PAb, Antigen Affinity Purified

  • Background
    Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses.
  • References
    • Messmer B, et al. (2006) CD48 stimulation by 2B4 (CD244)-expressing targets activates human NK cells. J Immunol. 176(8): 4646-50
    • Milstein O, et al. (2008) Nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse. J Biol Chem. 283(49): 34414-22.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"