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  • Anti-Carboxypeptidase A1/CPA1 antibody
  • Anti-Carboxypeptidase A1/CPA1 antibody
  • Anti-Carboxypeptidase A1/CPA1 antibody

Anti-Carboxypeptidase A1/CPA1 antibody

Cat.#: 103570

Special Price 145.0 USD

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Product Information

  • Product Name
    Anti-Carboxypeptidase A1/CPA1 antibody
  • Documents
  • Description
    Rabbit polyclonal to Carboxypeptidase A1/CPA1
  • Tested applications
    ELISA, WB, IHC-P, IP
  • Species reactivity
    Human Carboxypeptidase A1 / CPA1
  • Alternative names
    0910001L12Rik antibody; Carboxypeptidase A1 antibody; Carboxypeptidase A1 antibody; Cpa antibody; CPA antibody; Cpa1 antibody; CPA1 antibody; Cpa antibody; 0910001L12Rik antibody; CPA antibody
  • Immunogen
  • Isotype
    Rabbit IgG
  • Preparation
    Produced in rabbits immunized with purified, recombinant Human Carboxypeptidase A1 / CPA1 (rh Carboxypeptidase A1 / CPA1; NP_001859.1; Met 1-Tyr 419). Carboxypeptidase A1 / CPA1 specific IgG was purified by Human Carboxypeptidase A1 / CPA1 affinity chromatography.
  • Clonality
    Polyclonal
  • Formulation
    0.2 μm filtered solution in PBS with 5% trehalose
  • Storage instructions
    This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
    Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
  • Applications

    WB: 5-10 μg/mL

    ELISA: 0.1-0.2 μg/mL

    This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human CPA1. The detection limit for Human CPA1 is approximately 0.00975 ng/well.

    IHC-P: 0.1-1 μg/mL

    IP: 4-6 μg/mg of lysate

  • Validations

    Carboxypeptidase A1 / CPA1 Antibody, Rabbit PAb, Antigen Affinity Purified

    Carboxypeptidase A1 / CPA1 Antibody, Rabbit PAb, Antigen Affinity Purified

    Carboxypeptidase A1 / CPA1 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry

    Carboxypeptidase A1 / CPA1 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry

    Immunochemical staining of human CPA1 in human pancreas with rabbit polyclonal antibody (0.2 µg/mL, formalin-fixed paraffin embedded sections).

    Carboxypeptidase A1 / CPA1 Antibody, Rabbit PAb, Antigen Affinity Purified, Western blot

    Carboxypeptidase A1 / CPA1 Antibody, Rabbit PAb, Antigen Affinity Purified, Western blot

  • Background
    Human Carboxypeptidase A1 (CPA1)is secreted as a pancreatic procarboxypeptidase, and cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group, with the preference of  residues with aromatic or branched aliphatic side chains. CPA1 comprises a signal peptide, a pro region and a mature chain, and can be activated after cleavage of the pro peptide. In contrast to procarboxypeptidase B which was always secreted by the pancreas as a monomer, procarboxypeptidase A occurs as a monomer and/or associated to one or two functionally different proteins, such as zymogen E, and is involved in zymogen inhibition. Three different forms of human pancreatic procarboxypeptidase A have been isolated.
  • References
    • Catasus, L. et al., 1992, Biochem. J. 287: 299-303.
    • Moulard, M. et al., 1990, FEBS. Lett. 261: 179-183.
    • Aloy, P. et al., 1998, Biol. Chem. 379: 149-155.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"