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  • Anti-CA9 antibody

Anti-CA9 antibody

Cat.#: 142467

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Product Information

  • Product Name
    Anti-CA9 antibody
  • Documents
  • Description
    Rabbit Polyclonal to Human CA9
  • Tested applications
    WB, ELISA
  • Species reactivity
    Human Carbonic Anhydrase IX / CA9
  • Alternative names
    Car9 antibody; Carbonic Anhydrase 9 antibody; Carbonic Anhydrase IX antibody; Carbonic Anhydrase IX antibody; MN/CA9 antibody; RP23-195K8.9 antibody; MN antibody; CA9 antibody; CAIX antibody; CAIX antibody
  • Immunogen
  • Isotype
    Rabbit IgG
  • Preparation
    Produced in rabbits immunized with purified, recombinant Human Carbonic Anhydrase IX / CA9 . Carbonic Anhydrase IX / CA9 specific IgG was purified by Human Carbonic Anhydrase IX / CA9 affinity chromatography.
  • Clonality
    Polyclonal
  • Formulation
    0.2 μm filtered solution in PBS
  • Storage instructions
    This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
    Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
  • Applications

    WB: 5-20 μg/ml

    ELISA: 0.1-0.2 μg/ml

    This antibody can be used at 0.1-0.2 μg/ml with the appropriate secondary reagents to detect Human Carbonic Anhydrase IX / CA9.

  • Validations

    Human Carbonic Anhydrase IX/CA9 Western blot (WB) 14688

    Human Carbonic Anhydrase IX/CA9 Western blot (WB) 14688

  • Background
    Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA IX protein is expressed primarily in carcinoma cells lines, and the expression is cell density dependent and has been shown to be strongly induced by hypoxia, accordingly facilitates adaptation of tumor cells to hypoxic conditions. It is involved in tumorigenesis through many pathways, such as pH regulation and cell adhesion control. CA IX is used as a marker of tumor hypoxia and as a new therapeutic target for many human carcinomas and cancers.Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"