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  • Anti-ADAM15 antibody

Anti-ADAM15 antibody

Cat.#: 142182

Special Price 193.4 USD

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Product Information

  • Product Name
    Anti-ADAM15 antibody
  • Documents
  • Description
    Rabbit Monoclonal to Human ADAM15
  • Tested applications
    ELISA
  • Species reactivity
    Human ADAM15
  • Alternative names
    MDC15 antibody; MDC15 antibody; metargidin antibody; Adam15 antibody; ADAM15 antibody; MDC15 antibody; MDC15 antibody; metargidin antibody; RP11-540D14.1 antibody
  • Immunogen
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained from a rabbit immunized with purified, recombinant Human ADAM15 .
  • Clonality
    Monoclonal
  • Formulation
    0.2 μm filtered solution in PBS with 5% trehalose
  • Storage instructions
    This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
    Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
  • Applications

    ELISA(Cap): 0.5-4 µg/ml

    This antibody will detect Human ADAM15 in ELISA pair set . In a sandwich ELISA, it can be used as capture antibody when paired with .

  • Validations
  • Background
    ADAM15, also known as Metargidin, is a type I transmembrane glycoprotein belonging to the ADAM (A Disintegrin and Metalloprotease Domain) family of proteins and is widely expressed in different tissues and cell types. Members of this family contain an amino-terminal metalloprotease domain followed by a disintegrin domain, a cysteine-rich region and a membrane proximal EGF-like domain. The disintegrin domain of ADAM15/metargidin contains an RGD tripeptide sequence, suggesting that it may potentially interact with the integrin family of proteins. ADAM15 is a transmembrane multi-domain proteins implicated in proteolysis, cell-cell and cell-matrix interactions in various disease conditions. There is also evidence supporting a role for ADAM15 in angiogenesis and angioinvasion of tumor cells, which are critical for unrestrained tumor growth and metastatic spread. Given its diverse functions, ADAM15 may represent a pivotal regulatory component of tumor progression, an important target for therapeutic intervention, or emerge as a biomarker of disease progression.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"