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Product Name
Human ADAMTSL1 (His Tag) recombinant protein
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Description
ADAMTSL1 is a secreted molecule resembling members of the ADAMTS protein family of matrix metalloproteinases. Both ADAMTS proteins and ADAM protein family contain a disintegrin and a metalloprotease domain. Metallospondins is collective term for members of ADAMTS protein family. ADAMTS proteins lack the EGF-like domain found normally in members of the ADAM protein family. They also do not possess the canonical disintegrin sequence found in the ADAM protein family. It contains the domains found in members of the ADAMTS protein family with the exception of the pro-metalloprotease and the disintegrin-like domain typical of this family. ADAMTSL1 gene is expressed in adult skeletal muscle. ADAMTSL1 may play an important role in the extracellular matrix as it is deposited in the cell substratum in a punctate fashion and is excluded from focal contacts.
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Protein name
ADAMTS-like protein 1
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Protein short names
ADAMTS-LIKE PROTEIN 1; RP11-220B22.2; PUNCTIN; 6720426B09RIK; FLJ35283; 5930437A14RIK; MGC118805; DKFZP686L03130; C9ORF94; ADAM-TS RELATED PROTEIN 1; PUNCTIN-1; RP23-102G9.1; ADAMTSL-1; FLJ41032; MGC40193; FLJ46891; ADAMTSR1; MGC118803
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Uniprot ID
Q8N6G6
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Gene Name
ADAMTSL1; ADAMTSR1; C9orf94; UNQ528/PRO1071
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human ADAMTSL1 (Met 1-His439) (Q8N6G6-2) was expressed, with a C-terminal polyhistidine tag.
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Protein Species
Human
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Molecular weight
The secreted recombinant human ADAMTSL1 consists of 421 amino acids and predicts a molecular mass of 47 KDa. The apparent molecular mass of the protein is approximately 48 Kda in SDS-PAGE under reducing conditions due to glycosylation.
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Purity
> 97 % as determined by SDS-PAGE
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Validations
Human ADAMTSL1 / PUNCTIN Protein (His Tag) SDS-PAGE
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