Zyxin antibody

Zyxin antibody

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• Material Safety Data Sheets (MSDS)

Zyxin Mouse Monoclonal antibody. Positive WB detected in HeLa cells, A431 cells, MCF-7 cells. Positive IF detected in HeLa cells. Positive IHC detected in human kidney tissue, human breast cancer tissue, human cervical cancer tissue, human placenta tissue, human testis tissue. Observed molecular weight by Western-blot: 78kd

ELISA, WB, IHC, IF

Human,Mouse; other species not tested.

ESP 2 antibody; HED 2 antibody; ZYX antibody; zyxin antibody; Zyxin 2 antibody

Mouse IgG1

This antibody was obtained by immunization of Zyxin recombinant protein (Accession Number: NM_001010972). Purification method: Protein G purified.

Monoclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin (ZYX) is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles.