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Product Name
ZC3H12A antibody
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Description
ZC3H12A Rabbit Polyclonal antibody. Positive IP detected in Raji cells. Positive WB detected in Raji cells, mouse spleen tissue. Positive IHC detected in human small intestine tissue. Observed molecular weight by Western-blot: 66 kDa
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Tested applications
ELISA, WB, IHC, IP
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
dJ423B22.1 antibody; FLJ23231 antibody; MCP induced protein 1 antibody; MCPIP antibody; MCPIP1 antibody; Ribonuclease ZC3H12A antibody; RP3 423B22.1 antibody; ZC3H12A antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of ZC3H12A recombinant protein (Accession Number: NM_025079). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
IP: 1:200-1:1000
IHC: 1:20-1:200
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Validations
Raji cells were subjected to SDS PAGE followed by western blot with Catalog No:116923(ZC3H12A Antibody) at dilution of 1:300
IP Result of anti-ZC3H12A (IP:Catalog No:116923, 4ug; Detection:Catalog No:116923 1:300) with Raji cells lysate 2000ug.
Immunohistochemistry of paraffin-embedded human small intestine tissue slide using Catalog No:116923(ZC3H12A Antibody) at dilution of 1:50 (under 40x lens)
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Background
ZC3H12A, also named as MCPIP or MCPIP1, is a 599 amino acid protein, which contains one C3H1-type zinc finger and belongs to the ZC3H12 family. ZC3H12A localizes in the cytoplasm and nucleus. Increased expression of ZC3H12A is associated with ischemic heart disease. ZC3H12A has RNase activity and selectively degrades specific target mRNA species and modulates the immune response and inflammation by regulating the decay of specific mRNA molecules.
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