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Product Name
YES1-Specific antibody
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Description
YES1-Specific Rabbit Polyclonal antibody. Positive IP detected in human placenta tissue. Positive WB detected in human placenta tissue, HeLa cells. Positive IHC detected in human colon tissue. Observed molecular weight by Western-blot: 50-60 kDa
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Tested applications
ELISA, WB, IHC, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
c yes antibody; HsT441 antibody; P61 YES antibody; Proto oncogene c Yes antibody; Yes antibody; YES1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_005433). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:1000
IHC: 1:20-1:200
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Validations
human placenta tissue were subjected to SDS PAGE followed by western blot with Catalog No:116884(YES1-Specific antibody) at dilution of 1:300
Immunohistochemical of paraffin-embedded human colon using Catalog No:116884(YES1-Specific antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human colon using Catalog No:116884(YES1-Specific antibody) at dilution of 1:50 (under 40x lens)
IP Result of anti-YES1-Specific (IP:Catalog No:116884, 4ug; Detection:Catalog No:116884 1:300) with human placenta tissue lysate 1520ug.
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Background
YES1, also named as p61-Yes and YES, belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. It promotes infectivity of Neisseria gonorrhoeae in epithelial cells by phosphorylating MCP/CD46. YES1 catalyzes the reaction: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. The antibody is specific to YES1.
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References
- Li L, He L, Zhao JL. MiR-17-5p up-regulates YES1 to modulate the cell cycle progression and apoptosis in ovarian cancer cell lines. Journal of cellular biochemistry. 116(6):1050-9. 2015.
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