XAB2 antibody

XAB2 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

XAB2 Rabbit Polyclonal antibody. Positive WB detected in K-562 cells, HeLa cells. Positive IP detected in K-562 cells. Observed molecular weight by Western-blot: 100 kDa

ELISA, WB, IP

Human; other species not tested.

DKFZp762C1015 antibody; HCNP antibody; HCRN antibody; KIAA1177 antibody; NTC90 antibody; Pre mRNA splicing factor SYF1 antibody; Protein HCNP antibody; SYF1 antibody; XAB2 antibody; XPA binding protein 2 antibody

Rabbit IgG

This antibody was obtained by immunization of XAB2 recombinant protein (Accession Number: NM_020196). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

XPA-binding protein 2 (XAB2) a tetratricopeptide repeat protein involved in transcription-coupled DNA repair and transcription. XAB2 is involved in pre-mRNA splicing, transcription, and transcription-coupled DNA repair, leading to preimplantation lethality, and is essential for mouse embryogenesis. It interactes with Cockayne syndrome groups A and B (CSA and CSB) proteins and RNA polymerase II, which are known to be involved in transcription-coupled repair (TCR) and transcription, and that the antibodies against XAB2 protein inhibited the recovery of RNA synthesis after UV irradiation and normal RNA synthesis when microinjected into living fibroblasts.

• Lei H, Zhai B, Yin S, Gygi S, Reed R. Evidence that a consensus element found in naturally intronless mRNAs promotes mRNA export. Nucleic acids research. 41(4):2517-25. 2013.