WWP2 antibody

WWP2 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

WWP2 Rabbit Polyclonal antibody. Positive WB detected in mouse liver tissue, A549 cells. Positive IHC detected in human pancreas cancer tissue. Observed molecular weight by Western-blot: 110-115 kDa

ELISA, WB, IHC

Human, Mouse; other species not tested.

AIP2 antibody; WW domain containing protein 2 antibody; WWP2 antibody; WWp2 like antibody

Rabbit IgG

This antibody was obtained by immunization of WWP2 recombinant protein (Accession Number: XM_017022880). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

WWP2(WW domain-containing protein 2) is also named as AIP2 and belongs to the NEDD4-like protein family. It functions as an E3 ubiquitin ligase for PTEN that plays a vital role in tumour-cell survival and is also involved in regulating transcription, embryonic stem-cell fate, cellular transport and T-cell activation processes(PMID:21532586).WWP2, which specifically interacted with ES cell-specific transcription factor oct-4 and promoted its ubiquitination both in vitro and in vivo, is a ubiquitously expressed protein and exists in both cytoplasmic and nuclear compartments in ES cells(PMID:15047715).