WISP1 antibody

WISP1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

WISP1 Rabbit Polyclonal antibody. Positive IHC detected in human heart tissue, human kidney tissue, human small intestine tissue, mouse heart tissue. Positive WB detected in rat kidney tissue, mouse liver tissue, rat lung tissue. Positive IP detected in mouse kidney tissue. Observed molecular weight by Western-blot: 40-46 kDa

ELISA, IHC, IP, WB

Human,Mouse,Rat; other species not tested.

CCN family member 4 antibody; CCN4 antibody; WISP 1 antibody; WISP1 antibody; WISP1c antibody; WISP1i antibody; WISP1tc antibody; Wnt 1 induced secreted protein antibody

Rabbit IgG

This antibody was obtained by immunization of WISP1 recombinant protein (Accession Number: NM_003882). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

WISP1( Wnt-induced secreted protein 1), also known as CCN4, is a secreted, matricellular protein allocated to the CCN protein family. The CCN protein family consists of six, modular structured, secreted proteins ( Cyr61, CTGF, Nov, WISP1, WISP2, WISP3 ). WISP1 may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. WISP1 is expressed at a high level in fibroblast cells, and overexpressed in colon tumors. Its expression is associated with proliferation, cytoprotection, as well as extracellular matrix production. This antibody got a 55kDa band in western blotting, similar to the results obtained by the articles ( PMID:19287097 and PMID:15331410), and the 66 kDa may be an unspecific band.

• Yang JY, Yang MW, Huo YM. High expression of WISP-1 correlates with poor prognosis in pancreatic ductal adenocarcinoma. American journal of translational research. 7(9):1621-8. 2015.