WDR4 antibody

Cat.#: 116866

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Product Information

  • Product Name
    WDR4 antibody
  • Documents
  • Description
    WDR4 Rabbit Polyclonal antibody. Positive WB detected in HeLa cells, transfected cells, Transfected HEK-293 cells. Observed molecular weight by Western-blot: 30kd
  • Tested applications
    ELISA, WB
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    TRM82 antibody; WD repeat containing protein 4 antibody; WD repeat domain 4 antibody; WDR4 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of WDR4 recombinant protein (Accession Number: NM_001260476). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

  • Validations

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:116866(WDR4 antibody) at dilution of 1:300

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:116866(WDR4 antibody) at dilution of 1:300

    Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:116866(WDR4 Antibody) at dilution of 1:1000

    Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:116866(WDR4 Antibody) at dilution of 1:1000

  • Background
    A group of functionally diverse regulatory proteins in eukaryotes, defined by a conserved core of 4 or more modular repeat units, is known as the WD repeat family. Proteins belonging to the WD repeat family are involved in a number of cellular processes, including cell cycle progression, apoptosis, signal transduction, and gene regulation. WD repeat-containing protein 4 (WDR4) belongs to the WD repeat family, and is required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. It acts to stablize and induce conformation change of the catalytic subunit in the complex. There exists three isoforms, while isoform1, 2 are 45kDa band, and isoform 3 is 30 kDa band.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"