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Product Name
WDR1 antibody
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Description
WDR1 Rabbit Polyclonal antibody. Positive WB detected in rat skeletal muscle tissue, mouse skeletal muscle tissue. Positive IP detected in mouse skeletal muscle tissue. Positive IHC detected in human testis tissue. Observed molecular weight by Western-blot: 66-70 kDa
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Tested applications
ELISA, IHC, IP, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
Actin interacting protein 1 antibody; AIP1 antibody; NORI 1 antibody; WD repeat containing protein 1 antibody; WD repeat domain 1 antibody; WDR1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of WDR1 recombinant protein (Accession Number: NM_005112). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:2000
IHC: 1:20-1:200
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Validations
Immunohistochemical of paraffin-embedded human testis using Catalog No:116854(WDR1 antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human testis using Catalog No:116854(WDR1 antibody) at dilution of 1:100 (under 40x lens)
rat skeletal muscle tissue were subjected to SDS PAGE followed by western blot with Catalog No:116854(WDR1 Antibody) at dilution of 1:600
IP Result of anti-WDR1 (IP:Catalog No:116854, 3ug; Detection:Catalog No:116854 1:500) with mouse skeletal muscle tissue lysate 3600ug.
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Background
WDR1 represents WD repeat domain 1
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References
- Yuan B, Wan P, Chu D. A cardiomyocyte-specific Wdr1 knockout demonstrates essential functional roles for actin disassembly during myocardial growth and maintenance in mice. The American journal of pathology. 184(7):1967-80. 2014.
- Xu J, Wan P, Wang M. AIP1-mediated actin disassembly is required for postnatal germ cell migration and spermatogonial stem cell niche establishment. Cell death & disease. 6:e1818. 2015.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"