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Product Name
WBS15/LAT2 antibody
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Description
WBS15/LAT2 Rabbit Polyclonal antibody. Positive IHC detected in human prostate cancer tissue. Positive WB detected in mouse brain tissue, human brain tissue, human placenta tissue, Raji cells. Observed molecular weight by Western-blot: 27-30 kDa
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Tested applications
ELISA, IHC, WB
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
HSPC046 antibody; LAB antibody; LAT2 antibody; Non T cell activation linker antibody; NTAL antibody; WBS15 antibody; WBSCR15 antibody; WBSCR5 antibody; WSCR5 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of WBS15/LAT2 recombinant protein (Accession Number: NM_032463). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:116849(LAT2 antibody) at dilution of 1:1000
Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:116849(LAT2 antibody) at dilution of 1:50 (under 10x lens)
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Background
WBS15, also named as LAB, NTAL, WBSCR15, WBSCR5and LAT2 (Linker for activation of T-cells family member 2; not SLC7A8/LAT2), is involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast and myeloid cells. WBS15 is involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells. It is located in the Williams-Beuren syndrome (WBS) critical region. WBS15 has two isoform with MW 27-30 kDa and 12 kDa.
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