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Product Name
USP2 antibody
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Description
USP2 Rabbit Polyclonal antibody. Positive IF detected in HepG2 cells. Positive IHC detected in human liver tissue. Positive WB detected in mouse testis tissue, DU 145 cells. Observed molecular weight by Western-blot: 68kd
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Tested applications
ELISA, WB, IHC, IF
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
Deubiquitinating enzyme 2 antibody; ubiquitin specific peptidase 2 antibody; Ubiquitin thiolesterase 2 antibody; UBP41 antibody; USP2 antibody; USP9 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of USP2 recombinant protein (Accession Number: XM_005271721). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
IF: 1:10-1:100
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Validations
mouse testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:116597(USP2 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human liver using Catalog No:116597(USP2 antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human liver using Catalog No:116597(USP2 antibody) at dilution of 1:50 (under 40x lens)
Immunofluorescent analysis of HepG2 cells, using USP2 antibody Catalog No:116597 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
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Background
Ubiquitin, a highly conserved protein involved in the regulation of intracellular protein breakdown, cell cycle regulation, and stress response, is released from degraded proteins by disassembly of the polyubiquitin chains. The disassembly process is mediated by ubiquitin-specific proteases (USPs). USP2 is also named as UBP41. USP2 can interact indirectly with multiple clock proteins, so it remains possible that USP2 may modulate the ubiquitination and function of these other proteins. It has 4 isoforms produced by alternative splicing.
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