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Product Name
UNC5D-Specific antibody
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Description
UNC5D-Specific Rabbit Polyclonal antibody. Positive WB detected in mouse kidney tissue. Observed molecular weight by Western-blot: 59-65kd
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Tested applications
ELISA, WB
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Species reactivity
human, mouse; other species not tested.
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Alternative names
UNC5D antibody; Protein unc 5 homolog D antibody; FLJ16019 antibody; KIAA1777 antibody; Netrin receptor UNC5D antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_080872). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
mouse kidney tissue were subjected to SDS PAGE followed by western blot with Catalog No:116619(UNC5D-Specific antibody) at dilution of 1:500
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Background
UNC5D, also named as KIAA1777 and UNC5H4, belongs to the unc-5 family. It is a receptor for netrin. It may be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. The antibody is specific to UNC5D.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"