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Product Name
UNC119 antibody
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Description
UNC119 Rabbit Polyclonal antibody. Positive IF detected in MDCK cells.
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Tested applications
ELISA, IF
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Species reactivity
Human,Mouse,Rat, Dog; other species not tested.
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Alternative names
HRG4 antibody; Protein unc 119 homolog A antibody; Retinal protein 4 antibody; RG4 antibody; unc 119 homolog (C. elegans) antibody; UNC119 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of UNC119 recombinant protein (Accession Number: NM_005148). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
IF: 1:10-1:100
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Validations
Immunofluorescent analysis of MDCK cells using Catalog No:116571(UNC119 Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Background
Human UNC119 protein shares strong homology with the C. elegans unc119 protein which was first discovered in C. elegans on the basis of a spontaneous mutation affecting locomotion, feeding behavior and chemosensation. UNC119 is predominantly expressed in retina, in photoreceptor synapses and inner segments, with much lower expression in several other tissues. UNC119 is involved in the mechanism of photoreceptor neurotransmitter release through the synaptic vesicle cycle. It is required for G protein trafficking in sensory neurons.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"