UHMK1 antibody

UHMK1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

UHMK1 Rabbit Polyclonal antibody. Positive IHC detected in human prostate cancer tissue. Positive WB detected in mouse thymus tissue, mouse brain tissue. Positive IP detected in mouse brain tissue. Observed molecular weight by Western-blot: 47kd

ELISA, WB, IHC, IP

Human,Mouse,Rat; other species not tested.

KIS antibody; Kist antibody; U2AF homology motif kinase 1 antibody; UHMK1 antibody

Rabbit IgG

This antibody was obtained by immunization of UHMK1 recombinant protein (Accession Number: NM_144624). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

UHMK1, also named as KIS, or KIST, is a 419 amino acid protein, which contains one RRM (RNA recognition motif) domain, one protein kinase domain, and belongs to the protein kinase superfamily. UHMK1 is widely expressed, with highest levels in skeletal muscle, kidney, placenta and peripheral blood leukocytes. UHMK1 localizes in the nucleus and upon serum stimulation, phosphorylating CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. UHMK1 may be involved in trafficking and/or processing of RNA and may have a role in the developing nervous system and the adult brain.

• Rowe DD, Leonardo CC, Hall AA. Cord blood administration induces oligodendrocyte survival through alterations in gene expression. Brain research. 1366:172-88. 2010.