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UBE2L3 antibody

Cat.#: 116530

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Product Information

  • Product Name
    UBE2L3 antibody
  • Documents
  • Description
    UBE2L3 Rabbit Polyclonal antibody. Positive IP detected in mouse kidney tissue. Positive WB detected in HeLa cells, A431 cells, HEK-293 cells, K-562 cells, MCF7 cells, mouse kidney tissue, mouse testis tissue, NIH/3T3 cells, rat kidney tissue. Observed molecular weight by Western-blot: 18 kDa
  • Tested applications
    ELISA, WB, IP
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    E2 F1 antibody; L UBC antibody; UBCE7 antibody; UBCH7 antibody; UbcM4 antibody; UBE2L3 antibody; Ubiquitin carrier protein L3 antibody; Ubiquitin protein ligase L3 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of UBE2L3 recombinant protein (Accession Number: NM_003347). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:1000-1:10000

    IP: 1:1000-1:10000

  • Validations

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:116530(UBE2L3 antibody) at dilution of 1:500

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:116530(UBE2L3 antibody) at dilution of 1:500

    IP Result of anti-UBE2L3 (IP:Catalog No:116530, 3ug; Detection:Catalog No:116530 1:2000) with mouse kidney tissue lysate 4000ug.

    IP Result of anti-UBE2L3 (IP:Catalog No:116530, 3ug; Detection:Catalog No:116530 1:2000) with mouse kidney tissue lysate 4000ug.

  • Background
    UBE2L3(Ubiquitin-conjugating enzyme E2 L3) is also named as UBCE7, UBCH7 and belongs to the ubiquitin-conjugating enzyme family. It regulates nuclear hormone receptors transcriptional activity and may play a role in myelopoiesis.UBE2L3 is associated with susceptibility to systemic lupus erythematosus (SLE) and rheumatoid arthritis in European ancestry populations(PMID:22045845).
  • References
    • Fiesel FC, Moussaud-Lamodière EL, Ando M, Springer W. A specific subset of E2 ubiquitin-conjugating enzymes regulate Parkin activation and mitophagy differently. Journal of cell science. 127(Pt 16):3488-504. 2014.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"