TXNL1 antibody

TXNL1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

TXNL1 Rabbit Polyclonal antibody. Positive IP detected in HL-60 cells. Positive WB detected in K-562 cells, HL-60 cells. Observed molecular weight by Western-blot: 32 kDa

ELISA, WB, IP

Human,Mouse,Rat; other species not tested.

thioredoxin like 1 antibody; Thioredoxin like protein 1 antibody; TRP32 antibody; Txl antibody; TXL 1 antibody; TXNL antibody; TXNL1 antibody

Rabbit IgG

This antibody was obtained by immunization of TXNL1 recombinant protein (Accession Number: XM_017026093). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

TXNL1(Thioredoxin-like protein 1) is also named as TRP32, TXL, TXNL and belongs to the thioredoxin family. It might be involved in the cellular response to sugar starvation stress. The predicted 289-amino acid, 32.3-kD protein has 2 distinct domains: an N-terminal domain, which is 43% identical to human TXN, and a C-terminal domain, which showed no homology to other proteins in the sequence databases(PMID:9473519).TXNL1 functions as an effector of oxidants or redox sensor that couples oxidative stress to endocytosis, by converting redox changes into a specific GDI:Rab5-mediated endocytic response(PMID:17987124).

• Xu W, Wang S, Chen Q. TXNL1-XRCC1 pathway regulates cisplatin-induced cell death and contributes to resistance in human gastric cancer. Cell death & disease. 5:e1055. 2014.