TWSG1 antibody

Cat.#: 116504

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Product Information

  • Product Name
    TWSG1 antibody
  • Documents
  • Description
    TWSG1 Rabbit Polyclonal antibody. Positive WB detected in SH-SY5Y cells, A549 cells, C6 cells, mouse brain tissue, mouse thymus tissue, Raji cells. Positive IHC detected in mouse brain tissue, human kidney tissue. Observed molecular weight by Western-blot: 45 kDa
  • Tested applications
    ELISA, IHC, WB
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    TSG antibody; TWSG1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of TWSG1 recombinant protein (Accession Number: NM_020648). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:1000

    IHC: 1:20-1:200

  • Validations

    SH-SY5Y cells were subjected to SDS PAGE followed by western blot with Catalog No:116504(TWSG1 Antibody) at dilution of 1:300

    SH-SY5Y cells were subjected to SDS PAGE followed by western blot with Catalog No:116504(TWSG1 Antibody) at dilution of 1:300

    Immunohistochemistry of paraffin-embedded mouse brain tissue slide using Catalog No:116504(TWSG1 Antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemistry of paraffin-embedded mouse brain tissue slide using Catalog No:116504(TWSG1 Antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemistry of paraffin-embedded human kidney tissue slide using Catalog No:116504(TWSG1 Antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemistry of paraffin-embedded human kidney tissue slide using Catalog No:116504(TWSG1 Antibody) at dilution of 1:50 (under 40x lens)

  • Background
    Bone morphogenetic proteins (BMPs) are potent morphogens that are involved in cell fate determination, proliferation, apoptosis and adult tissue homeostasis. Twisted gastrulation (TWSG1) is a secreted BMP binding protein that modulates BMP ligand availability in the extracellular space. Several in vitro studies point toward an important role of TWSG1 in the regulation of the immune system (PMID: 21572028). The MW of this protein is 45 kDa, and this antibody specially recognises the 45 kDa protein.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"