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Product Name
Human TACI/TNFRSF13B(CD267) (His Tag) recombinant protein
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Description
Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.
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Protein name
Tumor necrosis factor receptor superfamily member 13B
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Protein short names
IGAD2; MGC39952; CD267; CVID2; TNFRSF14B; CVID; TACI; MGC133214; FLJ39942; RP23-55I2.2; TNFRSF13B; RYZN; 1200009E08RIK
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Uniprot ID
O14836
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Gene Name
TNFRSF13B; TACI
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human TNFRSF13B isoform 2 (O14836-2) extracellular domain (Ser 2-Thr 120) was expressed, with a polyhistidine tag at the C-terminus and a signal peptide at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human TNFRSF13B consists of 130 amino acids and has a predicted molecular mass of 14.8 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhTNFRSF13B is approximately 18-24 kDa.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human TNFRSF13B / TACI / CD267 Protein (His Tag) SDS-PAGE
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