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Product Name
TSPAN5 antibody
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Description
TSPAN5 Rabbit Polyclonal antibody. Positive WB detected in human brain tissue. Observed molecular weight by Western-blot: 30-40kd,90kd
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
NET 4 antibody; NET4 antibody; Tetraspan NET 4 antibody; tetraspanin 5 antibody; TM4SF9 antibody; TSPAN 5 antibody; TSPAN5 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of TSPAN5 recombinant protein (Accession Number: NM_005723). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:116363(TSPAN5 antibody) at dilution of 1:300
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Background
TSPAN5 is a membrane protein of the tetraspanin superfamily, which are characterized by the presence of four conserved transmembrane regions. Tetraspanins have been involved in diverse processes such as cell activation and proliferation, adhesion and motility, differentiation, and cancer. TSPAN5 belongs to the TSPANC8 subfamily, which also include TSPAN10, TSPAN14, TSPAN15, TSPAN17, and TSPAN33. It has been reported that TSPANC8 tetraspanins interact with ADAM10 and have a conserved function in the regulation of ADAM10 trafficking and activity, thereby positively regulating Notch receptor activation (PMID: 23091066; 23035126).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"