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Product Name
TSPAN15 antibody
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Description
TSPAN15 Rabbit Polyclonal antibody. Positive WB detected in human ovary cancer. Positive IHC detected in human ovary tumor tissue. Observed molecular weight by Western-blot: 33kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human; other species not tested.
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Alternative names
2700063A19Rik antibody; NET 7 antibody; NET7 antibody; Tetraspan NET 7 antibody; tetraspanin 15 antibody; TM4SF15 antibody; Tspan 15 antibody; TSPAN15 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of TSPAN15 recombinant protein (Accession Number: NM_012339). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
human ovary cancer were subjected to SDS PAGE followed by western blot with Catalog No:116446(TSPAN15 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human ovary tumor using Catalog No:116446(TSPAN15 antibody) at dilution of 1:100 (under 10x lens)
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Background
TSPAN15 is a membrane protein of the tetraspanin superfamily, which are characterized by the presence of four conserved transmembrane regions. Tetraspanins have been involved in diverse processes such as cell activation and proliferation, adhesion and motility, differentiation, and cancer. TSPAN15 belongs to the TSPANC8 subfamily, which also include TSPAN5, TSPAN10, TSPAN14, TSPAN17, and TSPAN33. It has been reported that TSPANC8 tetraspanins interact with ADAM10 and have a conserved function in the regulation of ADAM10 trafficking and activity, thereby positively regulating Notch receptor activation (PMID: 23091066; 23035126).
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