-
Product Name
TSPAN1 antibody
- Documents
-
Description
TSPAN1 Rabbit Polyclonal antibody. Positive IHC detected in human colon tissue. Positive WB detected in HeLa cells, COLO 320 cells, rat colon tissue. Observed molecular weight by Western-blot: 26-35kd
-
Tested applications
ELISA, WB, IHC
-
Species reactivity
Human, Mouse, Rat; other species not tested.
-
Alternative names
9030418M05Rik antibody; NET 1 antibody; RP11 322N21.1 antibody; Tetraspan NET 1 antibody; tetraspanin 1 antibody; Tetraspanin TM4 C antibody; TSPAN 1 antibody; TSPAN1 antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of TSPAN1 recombinant protein (Accession Number: NM_005727). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:200-1:1000
IHC: 1:20-1:200
-
Validations
HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:116440(TSPAN1 antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human colon tissue slide using Catalog No:116440(TSPAN1 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human colon tissue slide using Catalog No:116440(TSPAN1 Antibody) at dilution of 1:50 (under 40x lens)
-
Background
TSPAN1 is a membrane protein of the tetraspanin superfamily, which are characterized by the presence of four conserved transmembrane regions. Tetraspanins have been involved in diverse processes such as cell activation and proliferation, adhesion and motility, differentiation, and cancer. Altered TSPAN1 expression has been associated with the progression in some neoplasms including hepatocellular carcinoma, colorectal, gastric and breast cancers (PMID: 20890423; 19437569; 18822690; 20680643).
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"