-
Product Name
TRPC4AP antibody
- Documents
-
Description
TRPC4AP Mouse Monoclonal antibody. Positive IHC detected in human breast cancer tissue, human liver tissue. Positive WB detected in human brain tissue, human heart tissue. Observed molecular weight by Western-blot: 82 kDa
-
Tested applications
ELISA, WB, IHC
-
Species reactivity
Human; other species not tested.
-
Alternative names
C20orf188 antibody; Protein TAP1 antibody; Protein TRUSS antibody; Trp4 assOCiated protein antibody; Trpc4 assOCiated protein antibody; TRPC4AP antibody; TRRP4AP antibody; TRUSS antibody
- Immunogen
-
Isotype
Mouse IgG3
-
Preparation
This antibody was obtained by immunization of TRPC4AP recombinant protein (Accession Number: XM_047440095). Purification method: Protein A purified.
-
Clonality
Monoclonal
-
Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
-
Validations
human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:107646(TRPC4AP antibody) at dilution of 1:1000
Immunohistochemical of paraffin-embedded human liver using Catalog No:107646(TRPC4AP antibody) at dilution of 1:50 (under 40x lens)
Immunohistochemistry of paraffin-embedded human breast cancer slide using Catalog No:107646(TRPC4AP Antibody) at dilution of 1:50
-
Background
TRPC4AP, also named as C20orf188 and TRRP4AP, is a substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. TRPC4AP participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. The calculated molecular weight of TRPC4AP is 91 kDa. Western blot analysis detected a protein of about 82 kDa expressed in several mouse cell lines and in a human promonocytic cell line.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"