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TRAPPC2 antibody

Cat.#: 116342

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Product Information

  • Product Name
    TRAPPC2 antibody
  • Documents
  • Description
    TRAPPC2 Rabbit Polyclonal antibody. Positive IP detected in PC-3 cells. Positive WB detected in human brain tissue, human liver tissue, human lung tissue, mouse brain tissue, mouse thymus tissue, PC-3 cells. Observed molecular weight by Western-blot: 16 kDa
  • Tested applications
    ELISA, WB, IP
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    hYP38334 antibody; MBP 1 interacting protein 2A antibody; MIP 2A antibody; SEDL antibody; Sedlin antibody; SEDLP antibody; SEDT antibody; TRAPPC2 antibody; TRAPPC2P1 antibody; TRS20 antibody; ZNF547L antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of TRAPPC2 recombinant protein (Accession Number: XM_011545565). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IP: 1:200-1:2000

  • Validations

    human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:116342(TRAPPC2 antibody) at dilution of 1:600

    human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:116342(TRAPPC2 antibody) at dilution of 1:600

    IP Result of anti-TRAPPC2 (IP:Catalog No:116342, 3ug; Detection:Catalog No:116342 1:500) with PC-3 cells lysate 2800ug.

    IP Result of anti-TRAPPC2 (IP:Catalog No:116342, 3ug; Detection:Catalog No:116342 1:500) with PC-3 cells lysate 2800ug.

  • Background
    TRAPPC2 is one component of the TRAPP multisubunit tethering complex involved in intracellular vesicle trafficking [PMID:21525244]. It acts as an adaptor for the TRAPP complex in mammalian cells, mediating interactions with both TRAPPC9 and TRAPPC8. It prevents transcriptional repression and induction of cell death by ENO1. Also it plays a role in vesicular transport from endoplasmic reticulum to Golgi.
  • References
    • Westlake CJ, Baye LM, Nachury MV. Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome. Proceedings of the National Academy of Sciences of the United States of America. 108(7):2759-64. 2011.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"