TRAF4 antibody

TRAF4 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

TRAF4 Rabbit Polyclonal antibody. Positive WB detected in Transfected HEK-293 cells. Positive IHC detected in human pancreas cancer tissue.

ELISA, IHC, WB

Human; other species not tested.

CART1 antibody; MLN 62 antibody; MLN62 antibody; RING finger protein 83 antibody; RNF83 antibody; TRAF4 antibody

Rabbit IgG

This antibody was obtained by immunization of TRAF4 recombinant protein (Accession Number: NM_004295). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

TRAF4 is the fourth member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with and mediate signal transduction from members of the TNF receptor superfamily. TRAF1 and TRAF2 are two related proteins that form a heterodimeric complex that associates with the cytoplasmic domain of the TNF-receptor type 2. The third member TRAF3 associates with the cytoplasmic domain of CD40. TRAF4 has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-KAPPA B activation. This protein also binds to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. TRAF4 thus, is thought to be involved in the oxidative activation of MAPK8/JNK.