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Product Name
TMEM11 antibody
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Description
TMEM11 Rabbit Polyclonal antibody. Positive WB detected in human placenta tissue, mouse placenta tissue. Observed molecular weight by Western-blot: 22 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
C17orf35 antibody; PM1 antibody; PMI antibody; Protein PM1 antibody; TMEM11 antibody; transmembrane protein 11 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of TMEM11 recombinant protein (Accession Number: NM_003876). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
human placenta tissue were subjected to SDS PAGE followed by western blot with Catalog No:116093(TMEM11 antibody) at dilution of 1:1000
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Background
TMEM11, also named as C17orf35 and PM1, belongs to the TMEM11 family. TMEM11 is a mitochondrial inner-membrane protein facing the matrix. It regulates mitochondrial morphogenesis independently of the DRP1/MFN fission/fusion pathways.(PMID:21274005)
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References
- Rival T, Macchi M, Arnauné-Pelloquin L. Inner-membrane proteins PMI/TMEM11 regulate mitochondrial morphogenesis independently of the DRP1/MFN fission/fusion pathways. EMBO reports. 12(3):223-30. 2011.
- Guarani V, McNeill EM, Paulo JA. QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology. eLife. 4:. 2015.
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