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Product Name
TINAG-Specific antibody
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Description
TINAG-Specific Rabbit Polyclonal antibody. Positive WB detected in mouse small intestine tissue, human kidney tissue, human placenta tissue. Positive IHC detected in human colon tissue. Observed molecular weight by Western-blot: 55kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
TIN AG antibody; TINAG antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_014464). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
mouse small intestine tissue were subjected to SDS PAGE followed by western blot with Catalog No:116060(TINAG-Specific antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human colon using Catalog No:116060(TINAG-Specific antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human colon using Catalog No:116060(TINAG-Specific antibody) at dilution of 1:100 (under 40x lens)
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Background
TINAG belongs to the peptidase C1 family. TINAG mediates adhesion of proximal tubule epithelial cells via integrins alpha3-beta1 and alphaV-beta3. It is a non catalytic peptidase C1 family protein. Antibodies against TINAG are found in sera of patients with tubulointerstitial nephritis, a rare autoimmune disorder that causes acute and chronic renal injury.It has 2 isoforms produced by alternative splicing. The antibody is specific to TINAG.
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