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Timp-3 antibody

Cat.#: 116141

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Special Price 239.0 USD

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Product Information

  • Product Name
    Timp-3 antibody
  • Documents
  • Description
    Timp-3 Rabbit Polyclonal antibody. Positive IHC detected in human breast cancer tissue, human kidney tissue, human lung cancer tissue, human oesophagus cancer tissue, human stomach tissue.
  • Tested applications
    ELISA, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    HSMRK222 antibody; K222 antibody; K222TA2 antibody; Metalloproteinase inhibitor 3 antibody; Protein MIG 5 antibody; SFD antibody; Timp 3 antibody; TIMP3 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Timp-3 recombinant protein (Accession Number: NM_000362). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    IHC: 1:20-1:200

  • Validations

    Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using Catalog No:116141(Timp-3 Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using Catalog No:116141(Timp-3 Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using Catalog No:116141(Timp-3 Antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using Catalog No:116141(Timp-3 Antibody) at dilution of 1:50 (under 40x lens)

  • Background
    TIMP3 represents TIMP metallopeptidase inhibitor 3
  • References
    • Baba Y, Yasuda O, Takemura Y. Timp-3 deficiency impairs cognitive function in mice. Laboratory investigation; a journal of technical methods and pathology. 89(12):1340-7. 2009.
    • Xu C, Hou Z, Zhan P. EZH2 regulates cancer cell migration through repressing TIMP-3 in non-small cell lung cancer. Medical oncology (Northwood, London, England). 30(4):713. 2013.
    • Liu B, Che Q, Qiu H. Elevated MiR-222-3p promotes proliferation and invasion of endometrial carcinoma via targeting ERα. PloS one. 9(1):e87563. 2014.
    • Peng X, Li HX, Shao HJ. Involvement of calcium-sensing receptors in hypoxia-induced vascular remodeling and pulmonary hypertension by promoting phenotypic modulation of small pulmonary arteries. Molecular and cellular biochemistry. 396(1-2):87-98. 2014.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"