TIMM13 antibody

TIMM13 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

TIMM13 Rabbit Polyclonal antibody. Positive WB detected in PC-3 cells. Positive IF detected in HepG2 cells. Observed molecular weight by Western-blot: 11kd

ELISA, WB, IF

Human; other species not tested.

ppv1 antibody; TIM13 antibody; TIM13B antibody; TIMM13 antibody; TIMM13A antibody; TIMM13B antibody

Rabbit IgG

This antibody was obtained by immunization of TIMM13 recombinant protein (Accession Number: NM_012458). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

TIMM13 gene, also known as TIM13, TIM13B, TIM M13A or TIMM13B, encodes mitochondrial import inner membrane translocase subunit Tim13 belonging to the small Tim family. TIM13 functions as mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Proteins of the intermembrane space (IMS) of mitochondria are typically synthesized without presequences. TIM13 contains four conserved cysteine residues that bind a zinc ion as cofactor. Import of TIM13 did not depend on the membrane potential or ATP hydrolysis. Upon import into mitochondria TIM13 adopted a stably folded conformation in the IMS.

• Di Fonzo A, Ronchi D, Lodi T. The mitochondrial disulfide relay system protein GFER is mutated in autosomal-recessive myopathy with cataract and combined respiratory-chain deficiency. American journal of human genetics. 84(5):594-604. 2009.