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THAP2 antibody

Cat.#: 116040

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Special Price 239.0 USD

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Product Information

  • Product Name
    THAP2 antibody
  • Documents
  • Description
    THAP2 Rabbit Polyclonal antibody. Positive IF detected in Hela cells, HepG2 cells. Positive WB detected in HEK-293 cells, HeLa cells, human brain tissue, mouse testis tissue. Observed molecular weight by Western-blot: 26-30kd
  • Tested applications
    ELISA, WB, IF
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    DKFZp564I0422 antibody; THAP2 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of THAP2 recombinant protein (Accession Number: NM_031435). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IF: 1:10-1:100

  • Validations

    HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:116040(THAP2 antibody) at dilution of 1:600

    HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:116040(THAP2 antibody) at dilution of 1:600

    Immunofluorescent analysis of Hela cells, using THAP2 antibody Catalog No:116040 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

    Immunofluorescent analysis of Hela cells, using THAP2 antibody Catalog No:116040 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

  • Background
    THAP2, also named as THAP domain-containing protein 2, is a 228 amino acid protein, which contains one THAP-type zinc finger. Members of the THAP (thanatos-associated protein) family of proteins contain a well conserved DNA-binding domain known as the THAP-type zinc finger motif. Proteins containing the THAP-type zinc finger motif are commonly involved in transcriptional regulation, cell-cycle control, apoptosis and chromatin modification
  • References
    • Leite KR, Morais DR, Reis ST. MicroRNA 100: a context dependent miRNA in prostate cancer. Clinics (São Paulo, Brazil). 68(6):797-802. 2013.
    • Morais DR, Reis ST, Viana N. The involvement of miR-100 in bladder urothelial carcinogenesis changing the expression levels of mRNA and proteins of genes related to cell proliferation, survival, apoptosis and chromosomal stability. Cancer cell international. 14(1):119. 2014.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"